产品货号：
Z32754
中文名称：
ACE抗体
英文名称：
Anti-ACE Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ACE Antibody |
| 指标别名 | ACE;ACE1;Angiotensin converting enzyme;CD143;DCP;DCP1;Dipeptidyl carboxypeptidase I;Kininase II;MVCD3 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,IHC,FCM |
| 基因名称 | ACE |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human ACE1 Converts angiotensin I to angiotensin II by release of the terminal His-Leu,this results in an increase of the vasoconstrictor activity of angiotensin.Also able to inactivate bradykinin,a potent vasodilator.Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. |
| 实际分子量 | 150～180KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Angiotensin-converting enzyme (ACE),an exopeptidase,is a circulating enzyme that participates in the body's renin-angiotensin system(RAS),which mediates extracellular volume (i.e.that of the blood plasma,lymph and interstitial fluid),and arterial vasoconstriction.It is secreted by pulmonary and renal endothelial cells and catalyzes the conversion of decapeptide angiotensin I to octapeptide angiotensin II.Using a DNA marker at the growth hormone gene locus,which they characterized as 'extremely polymorphic' and which showed no recombination with ACE,ACE was mapped to 17q22-q24,consistent with the in situ hybridization mapping to 17q23.ACE,or kininase II,is a dipeptidyl carboxypeptidase that plays an important role in blood pressure regulation and electrolyte balance by hydrolyzing angiotensin I into angiotensin II,a potent vasopressor,and aldosterone-stimulating peptide.The enzyme is also able to inactivate bradykinin,a potent vasodilator. |
| Uniprot ID | P12821 |
| 推荐稀释比 | Western blot (WB) 1:400～800 Immunohistochemistry in paraffin section (IHC) 1:20～100 Flow cytometry (FCM) 1:20 |
相关搜索：ACE抗体，ACE单抗，Anti-ACE Antibody